Fast State Artificial Colonic Fluid (FaSAC)
Artificial colonic fluid (sterile) is a solution that simulates the components of the colonic fluid and simulates human-fast state of colonic fluid with pH 7.6. The fast-state artificial colonic fluid is mainly composed of physiological components (bile salt and lipids), Tris, Maleic acid, minerals such as sodium, and chloride. phosphate, etc. This reagent is sterilized by 0.2 μm filtration.
It is used to study drug interactions and modified-release study of drug products intended for colonic delivery dissolve in fast-state colonic fluids.
Note
1. Simulated Colonic Fluid is a sterile solution and can be used directly.
2. Simulated Colonic Fluid, stored at 4 degrees, transported at room temperature.
3. This product is limited to the scientific research of professionals, cannot be used for clinical diagnosis or treatment, cannot be used for food or medicine, and cannot be stored in ordinary houses.
4. For your safety and health, please wear a lab coat and disposable gloves.
Fasted State Artificial Colonic Fluid (FaSAC)
Simulate the Distal Colon Environment in the Fasted State – pH ~7.6
Fasted State Artificial Colonic Fluid (FaSAC) is a physiologically relevant in vitro medium designed to replicate the colonic environment under fasted conditions. With a carefully balanced composition, FaSAC mimics the pH, ionic strength, and osmolarity of human colonic fluid when the digestive system is in a fasting state.
This fluid is ideal for researchers and developers working on:
- Controlled-release oral drug formulations
- Colonic absorption and permeability studies
- Microbiome and fermentation models
- In vitro simulation of gastrointestinal transit
Key Features:
- pH ~7.6: Reflects fasting colonic pH for accurate dissolution and stability studies
- Sterile-filtered and ready to use
- Reproducible and physiologically relevant
- Customizable formulations available upon request
Applications:
- Biopharmaceutical testing (e.g., BCS Class III/IV drugs)
- In vitro–in vivo correlation (IVIVC) models
- Simulation of colon-targeted drug delivery
Available in multiple volumes for laboratory and industrial research needs.
Note: For research use only. Not intended for human or animal consumption.
